A novel deep-wrinkle targeting serum to use as an alternative to or enhancer of injectable treatments. The concentrated anti-wrinkle serum combines neuropeptide Argirelox® with marine peptides to dramatically lessen the appearance of expression lines and visibly plump skin. Provides cumulative improvement with continued use.
Wrinkle-Off Serum is a new serum targeting area-specific deeper lines and wrinkles such as lip lines, chin and necklines, crow’s feet, and frown lines.

Wrinkle-Off Serum can be incorporated into any skin care regimen and its active ingredients improve the appearance of deeper lines in both people who have never had Botulinum toxin injections, as well as those who have and wish to enhance the effectiveness of the injections.*


10% Argirelox®: an award-winning wrinkle remedy that combines Acetyl Hexapeptide-8 and Pentatpeptide-18. Clinical testing shows that within 7 days of twice-daily use, expression lines decrease in appearance an average of 20% in depth and 16% in length. In addition, this combination of peptides has proven effective in clinical testing in subjects who do not have neurotoxin injections and enhances the anti-wrinkle effects in those who have had such treatments.

  • Acetyl Hexapeptide-8 (Argireline®): was developed as a topical Botulinum toxin enhancer or alternative to temporarily relax (instead of paralyzing) muscles that give rise to expression lines. Argireline® is clinically proven to be effective at lessening the appearance of expression lines in subjects who did not use injectable Botulinum toxin. Clinic
  • Pentapeptide-18: acts to block Calcium entry into nerves and make the nerves less effective at contracting muscles of expression.

Seacode®: reduces the appearance of lines and wrinkles and plumps skin appearance. A marine-derived ingredient, Seacode® provides topical filler-like benefits. In vitro-testing shows Seacode®:

  • supports collagen production for deep firming benefits
  • manufacturers a hyaluronic-like substance in the skin to smooth lines and creases


Apply product to targeted deeper lines, such as lip lines, chin and necklines, crow’s feet, and frown lines. Allow to dry for 30 seconds and follow with serum and moisturizer to the entire face. Repeat twice daily. Visible improvement is typically seen within several days to a week and improvement is enhanced with continued use.